When Hope Calls is a heartwarming drama series that follows the journey of two orphaned sisters, Lillian and Grace, who reunite as adults and open an orphanage in a small town in Western Canada in 1916. As they strive to provide a loving home for the children in their care, they must navigate the challenges of small-town life, rancher rivalries, and their own personal struggles with love and relationships. Despite the obstacles they face, Lillian and Grace remain determined to make a difference in the lives of those around them, filling their days with hope, laughter, and adventure.

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Some TV shows that have similar genres and were produced around the same time as When Hope Calls include A Man in Full, Lessons in Chemistry, The Newsroom, Normal People, The Good Wife, Chernobyl.