This Way Up follows the journey of a young woman named Áine as she rebuilds her life after a nervous breakdown. With the support of her protective sister Shona, Áine navigates her way through the ups and downs of relationships, work, and finding her place in the world. This heartwarming comedy series explores themes of mental health, family, and self-discovery, offering a fresh and relatable perspective on the struggles and triumphs of modern life.

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Some TV shows that have similar genres and were produced around the same time as This Way Up include What I Like About You, Jury Duty, Donny!, You're Whole, Big Mood, The Curse.