Rush follows the story of Dr. William Rush, a charismatic and unconventional doctor who has made a name for himself as a "concierge" physician to the rich and famous in Los Angeles. With a reputation for discretion and a willingness to do whatever it takes to help his clients, Rush has built a lucrative practice that allows him to live a life of luxury and excess. But when an old flame and his own conscience begin to stir things up, Rush must confront the emptiness of his high-flying lifestyle and decide if he's ready to make a change. With a cast of colorful characters, including his drug supplier Manny Maquis and his personal assistant Eve Parker, Rush takes viewers on a wild ride through the darker side of Hollywood's glamour and glitz.

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Some TV shows that have similar genres and were produced around the same time as Rush include Lessons in Chemistry, Chernobyl, Mad Men, Shardlake, Normal People, Nashville.