Chosen follows the story of Ian Mitchell, a doctor and father who is forced to participate in a twisted killing game when a mysterious box arrives at his doorstep. With a loaded gun and a photo of a stranger, Ian must kill within the next three days or risk losing everything. As he navigates this deadly game, Ian must also protect his daughter and ex-wife from the dangerous players who are also involved. With no escape from the game, Ian must use his wits to survive and uncover the truth behind the mysterious organization known as The Watchers.

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Some TV shows that have similar genres and were produced around the same time as Chosen include Fallout, Shōgun, 3 Body Problem, Dead Boy Detectives, The Last of Us, Person of Interest.