A young couple finds their dream home, but their newfound happiness is quickly disrupted by a raucous houseguest who refuses to leave. The guest's outrageous behavior leads to a turf war that ultimately ruins their house, their marriage, and their lives. As tensions escalate, the couple must fight to protect their home and their relationship from the destructive influence of their unwanted visitor.

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Some movies that have similar genres and were produced around the same time as Guest House include Good Mourning, The Intern, Prom Dates, Mean Girls, Ricky Stanicky, Bottoms.

Guest House was released for streaming on September 4, 2020.