After a mental breakdown, Liz returns home to find a young woman named Caitlin claiming to be her husband's daughter. Despite her initial reservations, Liz and her family welcome Caitlin into their home, but tensions soon rise as Liz becomes increasingly suspicious of Caitlin's true intentions and the strange dynamic between father and daughter raises red flags. As the situation escalates, Liz's grip on reality begins to slip, leaving her questioning who to trust and what lies beneath the surface of this mysterious family drama.

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Some movies that have similar genres and were produced around the same time as A Wife's Nightmare include Freaks, Gone Girl, Tinker Tailor Soldier Spy, The Skin I Live In, Coherence, The Killing of a Sacred Deer.