In a world where bioterrorism has become a constant threat, a special task force known as the BSAA (Bioterrorism Security Assessment Alliance) works to prevent the spread of deadly viruses. When a fearless enemy out for revenge unleashes a brutal and deadly new virus, BSAA captain Chris Redfield enlists the help of Agent Leon S. Kennedy and Professor Rebecca Chambers to bring down the death merchant and save New York City. As the virus spreads, turning people into zombies, the team races against time to find a cure and stop the carnage. But as they delve deeper into the mystery, they discover a web of conspiracy that threatens to consume them all. Can they stop the virus and uncover the truth before it's too late?

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Some movies that have similar genres and were produced around the same time as Resident Evil: Vendetta include Constantine: The House of Mystery, Spider-Man: Into the Spider-Verse, Raya and the Last Dragon, Strange World, Lupin the IIIrd: Jigen's Gravestone, Captain Underpants: Epic Choice-o-rama.

Resident Evil: Vendetta was released for streaming on June 20, 2017.