In the heart of Mumbai, a group of ambitious young Indians work the night shift as outsourced technical support workers, providing aid and advice to faraway places like Kentucky and California. As they navigate the complexities of American culture, they straddle two worlds - their traditional Indian homes and their emerging Western identities. Through their struggles and dreams, this documentary film offers a unique glimpse into the lives of those who are shaping the globalized world while still holding onto their roots.

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Some movies that have similar genres and were produced around the same time as John & Jane include Grizzly Man, 10 Questions for the Dalai Lama, The Crimson Wing: Mystery of the Flamingos.