In a world where ancient relics hold dangerous powers, a secret organization known as ARCAM Corporation must protect them from falling into the wrong hands. Their top agents, the Spriggan, must use their skills and teamwork to outwit and outmaneuver rival organizations and keep the relics safe. But as tensions rise and the stakes become higher, the Spriggan agents must confront the darker aspects of their mission and the true nature of the relics they protect. Will they be able to save humanity from the destructive power of the past, or will they succumb to the temptation of its power?

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Some TV shows that have similar genres and were produced around the same time as Spriggan include Mobile Suit Gundam Wing, Halo: The Fall of Reach, Basilisk, Mobile Suit Gundam: Iron-Blooded Orphans, Mobile Suit Gundam: The 08th MS Team, Sengoku Basara.