In the dark underbelly of suburban America, a 15-year-old girl is abducted and thrust into the horrific world of human trafficking. With little help from the authorities, her desperate mother and a former sex worker take matters into their own hands, racing against time to rescue her from the clutches of this deadly trade. As they delve deeper into the dangerous underworld, they must confront their own demons and fight for survival. Will they be able to save the girl before it's too late, or will she become just another lost soul in the human trafficking abyss?

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Some movies that have similar genres and were produced around the same time as Skin in the Game include The Equalizer 3, Anatomy of a Fall, Killers of the Flower Moon, The Unbearable Weight of Massive Talent, John Wick: Chapter 4, Girl in the Basement.