In "Reptilicus," a group of scientists in Denmark discover a prehistoric reptile's tail frozen in the ice. As they study it, the tail begins to regenerate into a full-sized monster, which escapes and goes on a destructive rampage through the countryside and cities. The monster, named Reptilicus, can fly, swim, and walk, and its impenetrable scales make it nearly impossible to kill. The scientists and military must work together to stop the beast before it destroys everything in its path. But as they finally manage to sedate it, the film ends with a hint that the monster may not be gone for good. Will Reptilicus rise again?

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Some movies that have similar genres and were produced around the same time as Reptilicus include Jack the Giant Killer, The Way West, Krakatoa, East of Java, Planet of the Apes, The Tarnished Angels, The Blue Max.